Hybrid vigor: in praise of the hinny
The awesome Susan Orlean on mules (subscription):
The mule’s commitment to survival is interesting in a Darwinian context, because mules–the hybrid result of mating a male donkey with a female horse–have an uneven number of chromosomes and are therefore sterile. Every mule, then, is sui generis; it leaves no legacy beyond itself, no radiating gene pool to mark its visit to this world…Even the sheer persistence of the breed seems a stroke of genius. Since a horse and a donkey rarely mate on their own, mules are essentially man-made. It has been a successful invention–in fact, mules are probably the most successful and enduring animal hybrid, with beefalo coming in a distant second.

I work as an Assistant Professor in the Duke University Institute for Genome Sciences & Policy (although this site and its content are my own).
In 2007 I became the fourth subject in Harvard geneticist George Church's Personal Genome Project. As the PGP moves forward, I am chronicling the dawn of personal genomics, that is, people obtaining their genomic information for whatever reason(s) and figuring out what to do with it. I am interested in the relevant technologies and especially the attendant privacy and other ethical/legal/social issues.
This blog may also discuss some of my non-genome interests or, to paraphrase Dwight Yoakam, "Guitars, Cadillacs, hillbilly music, etc etc."
The header image comes from the Liz Lerman Dance Exchange's multimedia performance piece, "Ferocious Beauty: Genome."