genomeboy.com

I can only hope that this is still active, because I’m sure every homeless hospital patient in New York would be glad to know that his/her genome is worth five gallons of gas, four Sunday Times, three six packs, and a partridge in a freaking pear tree.

The hospital plans to offer a $20 incentive to any patient who donates an eight-milliliter vial of blood to a new Biobank, a warehouse of DNA and plasma that is a central component of the hospital’s Institute for Personalized Medicine. “Personalized medicine,” an approach that incorporates molecular analysis into managing a patient’s health, has been touted as the future of medicine ever since scientists completed the map of the human genome in 2003.

Woo hoo! Muchos gracias, Mt. Sinai! Can I give 16 mls and get $40? Can I bring my kids in, too? How much for my dog’s lymphocytes?

Genetic Scientists Develop Sheep With Brain Of A Goat

“Vegas Solves Health Care Crisis!”

Although the price tag for genetic studies is dropping, clinicians’ expertise remains expensive, and that worries Brunner. “Certainly with the amount of money people are spending genotyping thousands of patients, they are finding that the quality of the phenotype data is crucial,” Brunner says. That’s why, he says, a ‘phenome project’ is needed to investigate connections between phenotypes. The idea has been proposed before but stalled for lack of funding.

How would you characterize the climate in the US art community after 9/11?
It has just been horrible. We’re talking about the government pressure on doing activities that are perfectly legal. We’re talking about activities that at one time in this country were considered a great idea, like amateur science. Say someone wants to have a laboratory in their house. I guess not a lot of people have that any more, so that’s weird. And because it’s weird, it’s suspicious. And because it’s suspicious, we have to think it’s probably terrorism.

- Bioartist and “public menace” Steve Kurtz

A genetic difference is often adaptive and can be regarded as an advance in the evolutionary process; it is well-known that autism sometimes brings with it remarkable powers in the areas of music, art and mathematics. In the 2006 movie “X-Men: The Last Stand,” the augmented powers of those known as “mutants” are even more remarkable and include the ability to walk through walls, to move metal objects as large as California’s Golden Gate Bridge, to auto-generate fire or ice, to be in seven places at the same time, to read minds, to assume any identity, to kill with a touch, to fly like Icarus, to change the weather. These abilities are seen by many “normal” human beings, and a few mutants, as disabilities, as an indication that the person who possesses one of them is a freak.

***

Within the minority community the conviction grows that its stigmatization is the result not of “natural” deficiencies, but of a politically established norm that serves the interests of the powers that be. Exposing that norm as a mere artifact of history with no special claim to authority means first that it is no longer obligatory to honor it, and second, that the community’s norms are worthy of both loyalty and protection. What was once seen as a deviation or something to be eradicated is re-characterized as a culture, and in a short time the culture has a lobby and is demanding respect, representation and even reparations for opportunities denied and rights withheld. The formerly shunned but now legitimized community opens cultural centers, galleries (think of graffiti artists), museums, historical archives, and soon it is being courted by the very mainstream constituencies that for so long accorded it only a negative recognition.

- Stanley Fish on stigmatization

“Senior scientists running labs don’t read journals; they say the younger people will tell them about anything important that gets published—if they haven’t heard about it beforehand anyway…”

- Michael Crichton in Slate

(l to r) Brian Greene, some photobomber, Paul Nurse, Nikolas Rose, Jim Evans, Francis Collins

The World Science Festival was as delightful as advertised. The street fair was overflowing with stuff to do, especially for kids. Next year I hope to bring mine. Bravo to Brian Greene!

I don’t know how my fellow panelists or the audience felt, but I thought our session, “Your Biological Biography,” was both fun and engaging, largely due to the masterful moderating job of Sir Paul Nurse, who is the antithesis of the stereotypical egocentric Nobel laureate/major university president. He is quick-witted, modest to a fault, and a brilliant conversationalist, someone you could chat with for hours on just about any subject. Drs. Rose, Evans and Collins responded in kind with thoughtful and nuanced discussion of personal genomics and all of the surrounding medical, legal, ethical and social issues. My only regret is that Dr. Latanya Sweeney was not able to make it and share her insights on genomic privacy.

I talked about getting my SNP data from George and from Navigenics, the limitations of it, SNPedia, my family history, my own curiosity, and how I’m probably not a terribly zealous early adopter after all. At the end I tried to make two points. One is that genome scientists themselves are succeeding in killing genetic determinism where bioethicists and philosophers have failed. That is, by finding that traits like type 2 diabetes and height are influenced by some ridiculous number of genes and the environment, genomicists are putting to rest the notion that single genes typically exert powerful, inexorable effects that determine who we are. Yeah, that happens in some cases, but complex traits are still complex, which makes accurate genetic predictions harder to achieve and genetic discrimination even harder to justify.

The other thing I tried to get across is that simply trashing personal genomics companies is not terribly helpful. Whatever their shortcomings (and they have plenty), these companies are here to stay in some way, shape or form. The more productive things to do, in my opinion, are to find out why people want this information, what their expectations are for it, how it should and shouldn’t be regulated, and how personal genomics, in all of its guises, can be assimilated by both the health care community and the public in useful ways.

A programming note: On Saturday afternoon I will be at the World Science Festival, which looks like more fun than people should be allowed to have. There I will infiltrate…pretend I belong on…annoy…er, appear on an otherwise esteemed panel, including Nobel laureate Paul Nurse, NHGRI Director Francis Collins (what the…?), computer scientist Latanya Sweeney, sociologist Nikolas Rose and geneticist Jim Evans. We will be talking about how personal genomics affects/will affect our lives; my genome and phenome (yawn) and, I expect, the PGP will be topics for discussion. Please stop by and say hello if you’re so inclined. (Thanks to the indefatigable Alison Snyder for making this panel happen.)

And even if genes and identity aren’t your thing, I encourage those in the NYC area to check out the rest of the Festival. Brian Greene, Tracy Day and company have done a masterful job in putting together an amazing program. It’s dork heaven. baby!

Comic lives here. Hat tip.