Nanopore-Based Single-Molecule Investigation of DNA Sequences with Potential to Form i-Motif Structures

Nanopore-Based Single-Molecule Investigation of DNA Sequences with Potential to Form i-Motif Structures

i-Motifs are DNA secondary buildings current in cytosine-rich sequences. These buildings are fashioned in regulatory areas of the human genome and play key regulatory roles. The investigation of sequences able to forming i-motif buildings on the single-molecule stage is very essential. On this examine, we used α-hemolysin nanopores to systematically examine a sequence of DNA […]